解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The aim of the present study was to monitor adverse drug reactions associated with antihypertensive drugs. The study was conducted in medicine out patient department of 150-bed Majeedia Hospital at Hamdard University Campus in New Delhi. The study was conducted by way of one to one patient interview by a registered ph...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.56018
更新日期:2009-05-01 00:00:00
abstract::Essential oils extracted from flower petals of palmarosa (Cymbopogon martini), evening primrose (Primula rosea), lavender (Lavandula angustifolia) and tuberose (Polianthus tuberosa) were tested for their antibacterial activities against gram-positive and gram-negative bacteria. Different concentrations of each essenti...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.54278
更新日期:2009-03-01 00:00:00
abstract::Floating matrix tablets of domperidone were developed to prolong gastric residence time and thereby increased drug bioavailability. Domperidone was chosen as a model drug because it is poorly absorbed from the lower gastrointestinal tract. The tablets were prepared by wet granulation technique, using polymers such as ...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.51944
更新日期:2009-01-01 00:00:00
abstract::A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for estimation of ropinirole hydrochloride in bulk and tablet dosage forms. Ropinirole hydrochloride shows maximum absorbance at 250 nm with molar absorptivity of 8.703x10(3) l/mol.cm. Beer's law was obeyed in the concentrati...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.51962
更新日期:2009-01-01 00:00:00
abstract::Several 4-arylidene-2-phenyl-1-(2,4,5-trichlorophenyl)-1H-imidazol-5(4H)-ones (4a-q), N-(4-benzylidene-5-oxo-2-phenyl-4,5-dihydroimidazol-1-yl)-4-chlorobenzamides (5a-o) and N-(4-benzylidene-5-oxo-2-phenyl-4,5-dihydroimidazol-1-yl)-2,4-dichlorobenzamides (6a-m) were prepared. All newly synthesized compounds have been ...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.51953
更新日期:2009-01-01 00:00:00
abstract::Ethyl naphtho[2,1-b]furan-2-carboxylate (2) on reaction with hydrazine hydrate in presence of acid catalyst in ethanol medium affords naphtho[2,1-b]furan-2-carbohydrazide (3). The reaction of substituted acetophenones (4a-c) with aromatic aldehydes (5a-e) produces chalcones (6a-o) via the Claisen condensation. The rea...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.49090
更新日期:2008-11-01 00:00:00
abstract::A series of novel isatine-sulphonamide derivatives have been synthesized by combining isatin derivatives with sulphonamides. The structure of the synthesized compounds were elucidated by spectral analysis (IR, NMR and Mass). Investigation of anti-HIV activity was done against HIV-1(IIIB) in MT-4 cells and HIV integras...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.49121
更新日期:2008-11-01 00:00:00
abstract::A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of bicalutamide in bulk and pharmaceutical dosage forms. Bicalutamide shows maximum absorbance at 272 nm with molar absorptivity of 2.3399×10(4) l/mol/cm. Beer's law was obeyed in the concentration range of...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.49131
更新日期:2008-11-01 00:00:00
abstract::Ethanol extract of leaves of Clerodendron phlomoidis L. subjected to preliminary qualitative phytochemical investigations showed the presence of alkaloids, phytosterols, glycosides, saponins, phenolic compounds, proteins and flavonoids. The extract was screened for hypoglycemic activity in alloxan-induced diabetic rat...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.49141
更新日期:2008-11-01 00:00:00
abstract::A set of seventy four molecules belonging to the class of thioglitazones were subjected to the QSAR analysis for their antihyperglycemic activity. All the molecules were subjected to energy minimization to get 3D structures, followed by conformational analysis to get the conformation of the molecule associated with th...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.45392
更新日期:2008-09-01 00:00:00
abstract::A mucoadhesive drug delivery system for systemic delivery of nitrendipine, a calcium channel blocker through buccal route was formulated. Mucoadhesive polymers like hydroxypropylmethylcellulose K-100, hydroxypropylcellulose, sodium carboxymethylcellulose, sodium alginate, polyvinyl alcohol, polyvinyl pyrrolidone K-30 ...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.45402
更新日期:2008-09-01 00:00:00
abstract::The effect of some physical and nutritional parameters were studied for the optimum production of extracellular enzyme hyaluronidase employing Streptococcus mitis MTCC*2695 by submerged fermentation. The effects of initial pH, incubation temperature and time, inoculum level and age of inoculum were studied. The maximu...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.45412
更新日期:2008-09-01 00:00:00
abstract::In the present investigation chitosan has been chemically modified by treating with two different aldehydes like acetaldehyde and propionaldehyde to form Schiff's bases. Schiff's bases of chitosan with acetaldehyde and propionaldehyde were named as polymer A and polymer B, respectively. Fourier Transform Infra Red (FT...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.44593
更新日期:2008-07-01 00:00:00
abstract::A simple accurate, sensitive and reproducible spectrofluorimetric method was developed for the analysis of duloxetine hydrochloride in pure and pharmaceutical dosage form. Duloxetine hydrochloride showed strong native fluorescence in 0.05 M acetic acid having excitation at 225 nm and emission at 340 nm. Effect of diff...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.44603
更新日期:2008-07-01 00:00:00
abstract::An oral controlled release suspension of chlorpheniramine maleate was prepared using ion-exchange resin technology. A strong cation exchange resin Indion 244 was utilized for the sorption of the drug and the drug resinates was evaluated for various physical and chemical parameters. The drug-resinate complex was microe...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.44613
更新日期:2008-07-01 00:00:00
abstract::Aqueous extract of leaves of Nelumbo nucifera was investigated on acute stress (immobilization stress)-induced biochemical alterations in Swiss mice. The animals were also subjected to acute physical stress (swimming endurance test) and acute chemical stress (writhing test) to gauge the antistress potential of the ext...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.42982
更新日期:2008-05-01 00:00:00
abstract::A simple, reproducible and efficient reverse phase high performance liquid chromatographic method was developed for simultaneous determination of valsartan and hydrochlorothiazide in tablets. A column having 200 x 4.6 mm i.d. in isocratic mode with mobile phase containing methanol:acetonitrile:water:isopropylalcohol (...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.43006
更新日期:2008-05-01 00:00:00
abstract::A rapid and sensitive reverse phase high performance liquid chromatographic method is depicted for the qualitative and quantitative assay of letrozole in pharmaceutical dosage forms. Letrozole was chromatographed on a reverse phase C18 column with a mobile phase consisting of acetonitrile and phosphate buffer (pH 7.8)...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.43019
更新日期:2008-05-01 00:00:00
abstract::Mitochondrial sodium calcium exchange inhibitors are novel agents in the treatment of type-II diabetes due to their glucose dependent efficacy. While the compounds of this class are expected to correct hyperglycemia, they do not lower basal blood glucose level, thus avoiding the serious consequences of hypoglycemia. T...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.41453
更新日期:2008-03-01 00:00:00
abstract::Duloxetine hydrochloride is a potent dual reuptake inhibitor of serotonin and norepinephrine used to treat major depressive disorders. The present work describes a simple, precise and accurate HPTLC method for its estimation as bulk and in tablet dosage form. The chromatographic separation was carried out on precoated...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.41463
更新日期:2008-03-01 00:00:00
abstract::A reverse phase high performance liquid chromatographic method was developed for the simultaneous estimation of atorvastatin calcium and fenofibrate in tablet formulation. The separation was achieved by Luna C18 column and methanol:acetate buffer pH 3.7 (82:18 v/v) as mobile phase, at a flow rate of 1.5 ml/min. Detect...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.41473
更新日期:2008-03-01 00:00:00
abstract::In the present study, 2,5-disubstituted-1,3,4-oxadiazoles (3a-o) have been synthesized by the condensation of 4-methoxybenzohydrazide (1) with different aromatic acids (2a-o) in presence of phosphoryl chloride. The structural assignment of this compound (3a-o) has been made on the basis of elemental analysis, UV, IR, ...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.40331
更新日期:2008-01-01 00:00:00
abstract::A high-performance liquid chromatographic method for the estimation of berberine in the stem of Tinospora cordifolia (Willd.) Miers. ex Hook.f. and Thoms. and Tinospora sinensis (Lour.) Merrill is described. The dried stems of T. cordifolia and T. sinensis were defatted with petroleum ether (60-80 degrees ). The marc ...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.40341
更新日期:2008-01-01 00:00:00
abstract::A novel, simple, sensitive and rapid spectrophotometric method has been developed for simultaneous estimation of esomeprazole and domperidone. The method involved solving simultaneous equations based on measurement of absorbance at two wavelengths, 301 nm and 284 nm, lambda max of esomeprazole and domperidone respecti...
journal_title:Indian journal of pharmaceutical sciences
pub_type: 杂志文章
doi:10.4103/0250-474X.40351
更新日期:2008-01-01 00:00:00